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Trinucleotide Repeat Expansion

The human genome contains tandem repeats of trinucleotides. Normally they occur in groups of 5–35 repeats. When their number exceeds a certain threshold and...

Transposition

Aside from homologous recombination, the overall stability of the genome is interrupted by mobile sequences called transposable elements or transposons. There are different classes...
Anemia self-test device

At-Home Anemia Test (60 seconds)

Anemia is usually defined as a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood. It can also be...
Recombinant DNA

Recombination

Recombination lends the genome flexibility. Without genetic recombination, the genes on each individual chromosome would remain fixed in their particular position. Changes could occur...
video

DNA Polymorphism

Genetic polymorphism is the existence of variants with respect to a gene locus (alleles), a chromosome structure(e.g., sizeofcentromeric heterochromatin), a gene product (variants in...
DNA mutation

Mutation Due to Different Base Modifications

Mutations can result from chemical or physical events that lead to base modification. When they affect the base-pairing pattern, they interfere with replication or transcription. Chemical substancees...
DNA mutation

Changes in DNA (Mutations)

When it was recognized that changes (mutations) in genes occur spontaneously (T. H. Morgan, 1910) and can be induced by X-rays (H. J. Muller,...
curcuma

Turmeric: a Natural Antidepressant more effective than Prozac

According to a recent clinical study published in the journal "Phytotherapy Research", it has been proven that this spice offers incredible health benefits. We...
video

DNA Amplification by Polymerase Chain Reaction (PCR)

The introduction of cell-free methods for multiplying DNA fragments of defined origin (DNA amplification) in 1985 ushered in a new era in molecular genetics...
Southern blot

Restriction Analysis by Southern Blot Analysis

Restriction endonucleases are DNA-cleaving enzymes with defined sequences as targets. They are often simply called restriction enzymes. Since each enzyme cleaves DNA only at...
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