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Bacteriophages

The discovery of bacterial viruses (bacteriophages or phages) in 1941 opened a new era in the study of the genetics of prokaryotic organisms. Although...

Recombination in Bacteria

In 1946, J. Lederberg and E. L. Tatum first demonstrated that genetic information can be exchanged between different mutant bacterial strains. This corresponds to...

Isolation of Mutant Bacteria

Important advances in genetics were made in the early 1950s through studies of bacteria. As prokaryotic organisms, bacteria have certain advantages over eukaryotic organisms...

Xeroderma Pigmentosum

Xeroderma pigmentosum (XP) is a heterogeneous group of genetically determined skin disorders due to unusual sensitivity to ultraviolet light. They are manifested by dryness...
DNA repair

DNA Repair

Life would not be possible without the ability to repair damaged DNA. Since replication errors, including mismatch, and harmful exogenous factors are everyday problems...

Trinucleotide Repeat Expansion

The human genome contains tandem repeats of trinucleotides. Normally they occur in groups of 5–35 repeats. When their number exceeds a certain threshold and...

Transposition

Aside from homologous recombination, the overall stability of the genome is interrupted by mobile sequences called transposable elements or transposons. There are different classes...
Anemia self-test device

At-Home Anemia Test (60 seconds)

Anemia is usually defined as a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood. It can also be...
Recombinant DNA

Recombination

Recombination lends the genome flexibility. Without genetic recombination, the genes on each individual chromosome would remain fixed in their particular position. Changes could occur...
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DNA Polymorphism

Genetic polymorphism is the existence of variants with respect to a gene locus (alleles), a chromosome structure(e.g., sizeofcentromeric heterochromatin), a gene product (variants in...
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